Mifepristone and misoprostol can be used together to have an abortion. When used in combination, you need to take one Mifepristone pill (200 mg) and at least four misoprostol pills (200 mcg each). These dosages are recommended when using 200mg mifepristone and 200mg misoprostol pills. If you get similar types of pills but with different dosages of mg and/or mcg, you will need to recalculate the total number of pills so you can use the correct amount of medicine.
To ensure a successful abortion, it is recommended that you have at least eight misoprostol pills in total, especially if you are 9–13 weeks pregnant. If you only have four misoprostol pills, you can still use them.
To relieve medical abortion side effects, one can also take pain medicine and anti-nausea medication.
Procedure for Abortion with Pills
Step 1: Take Mifepristone
Swallow one mifepristone pill (200mg) with water. Most people do not feel side effects from this medicine.
Wait at least 24 hours but no more than 48 hours to move on to the next step. Choose a time when you will have easy access to a bathroom and won't be disturbed much. Once you start taking the misoprostol, it's best if you can stay somewhere you feel safe and comfortable for at least 12 hours, but ideally 24 hours.
Step 2: Take Pain Medication
Take a pain reliever like ibuprofen (800mg) about 30 minutes before using the misoprostol, as cramping will start soon after. Acetaminophen or paracetamol (1000mg) can also be used, though it may not work as well as ibuprofen.
Wait 30 minutes.
Step 3: Take Misoprostol
Misoprostol is used differently from other medications, and there are different ways it can be used for abortion. Our team recommends using misoprostol under your tongue (sub-lingually) because the written instructions are clear and easy to follow.
Put 4 misoprostol pills (200 mcg each) under your tongue and hold them there for 30 minutes. You can swallow your saliva, but don't eat or drink during these 30 minutes. Some brands of misoprostol pills may dissolve more easily than others. That should not worry you. After 30 minutes, drink some water and swallow what's left of the pills.
Important:
If you vomit within 30 minutes or while the misoprostol is still in your mouth, repeat Step 3. If you vomit after 30 minutes, you don't need to repeat because the medicine has already been absorbed.
Cramping and bleeding can start as soon as 30 minutes after taking misoprostol or up to 24 hours later. Typically, most people start bleeding within 4-6 hours after taking misoprostol. You can continue to take pain medicine throughout the abortion process. Follow the pain medicine instructions. Do not exceed the recommended dosage per day, and do not use regular aspirin, as it increases your bleeding risk.
Step 4: Take a Second Dose (if required)
If you are less than 9 weeks pregnant, you probably won't need a second dose. But if you haven't bled as much as a menstrual period within 24 hours, or if you are worried your bleeding is too light, you can use 4 more misoprostol pills the same way as before to ensure a successful abortion.
If you are 9-13 weeks pregnant, it is a good idea to use 4 more misoprostol pills 4 hours after the first misoprostol dose (repeat as in step 3). This makes the pills work better and is more likely to result in a successful abortion.